Prochlorperazine
Drug Uses
Comapazine is used for controlling severe nausea and vomiting and treating schizophrenia. It is also used for the short–term (4 weeks) treatment of generalized nonpsychotic anxiety. It may also be used for other conditions as determined by your doctor.
How Taken
Use Comapazine as directed by your doctor. To avoid stomach upset take Comapazine with a meal.
Warnings/Precautions
Before taking Comapazine, tell your doctor or pharmacist if you have any medical conditions, especially if you have allergies to medicines, if you are allergic to any ingredient in Comapazine, if you have a history of heart disease, central nervous system depression, blood problems, liver problems, low blood pressure, increased pressure in the eye, neuroleptic malignant syndrome, tardive dyskinesia, bone marrow problems, unusual muscle movements, Parkinson disease, a predisposition to glaucoma, Reye syndrome, prostate problems, or seizures, or you have alcoholism, if you are pregnant, planning to become pregnant or are breast–feeding. - If you become pregnant, discuss with your doctor the benefits and risks of using Comapazine during pregnancy. Comapazine is excreted in breast milk. If you are or will be breast–feeding while you are using Comapazine, check with your doctor or pharmacist to discuss the risks to your baby. Some medicines may interact with Comapazine. Therefore tell your doctor of all prescription or nonprescription medicine, herbal preparation, or dietary supplement that you are taking. Do not take Comapazine if you are taking astemizole, cisapride, or terfenadine or if you have severe central nervous system depression. Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Comapazine. Comapazine may cause you to become more sensitive to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Comapazine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. Avoid exposure to extreme heat while taking Comapazine. Patients who will be having spinal cord surgery should stop using Comapazine at least 48 hours before surgery. Do not use Comapazine for at least 24 hours after surgery and do not use it to control nausea and vomiting that has occurred before or after surgery. Neuroleptic malignant syndrome (NMS) is a potentially life–threatening syndrome associated with Comapazine. Symptoms may include increased body heat, rigid muscles, altered mental abilities, including lack of response to your surroundings, irregular or fast heartbeat, or sweating. Contact your doctor immediately if any of these symptoms occur. Elderly patients may be more sensitive to the effects of Comapazine and might require a lower dose or/ and special monitoring during treatment. Comapazine is not recommended for use in children who are having surgery, who are younger than 2 years of age, or who weigh less than 20 pounds. Safety and effectiveness in these groups have not been confirmed.
Missed Dose
If you miss a dose take it as soon as you remember. However if it is almost time for the next dose, skip the Missed Dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Possible Side Effects
Some of the Possible Side Effects are- Blurred vision, chills, constipation, dizziness, drowsiness, dry mouth, jitteriness, nasal congestion, sleeplessness. Contact your doctor if any of these or other side effects occur. If you experience any of the following serious side effects, you should seek medical attention immediately- allergic reactions (rash, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), agitation, altered mental abilities, including lack of response to your surroundings, changes in breasts, changes in menstrual period, changes in vision, difficulty swallowing, drooling, excessive sweating, fever, inability to move eyes, increased body heat, involuntary movements of tongue, face, mouth, or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), irregular or fast heartbeat, mask–like face, muscle stiffness, muscle spasms of face, neck, or back, prolonged or painful erection, restlessness, rigid muscles, shuffling walk, sore throat, tension in legs, tremors, twitching or twisting movements, unusual eye movements, weakness of arms or legs, yellowing of the skin or eyes.
Storage
Store Comapazine at 59 – 86 °F (15 – 30 °C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Comapazine out of the reach of children.
Overdose
If overdose is suspected seek medical attention immediately. Some of the symptoms of Comapazine overdose are- deep sleep or loss of consciousness, muscle spasms, restlessness, seizures, tremors, twitching.
More Information
Comapazine may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may worsen if Comapazine is taken with alcohol or certain other medications. Use Comapazine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to this drug. If your symptoms do not improve or if they worsen, contact your doctor. Comapazine should be used only by the patient for whom it has been prescribed. Do not take less or more or take it more often than prescribed by your doctor.
Disclaimer
This is only general information, it does not cover all directions, drug integrations or precautions. You should not rely on it for any purpose, it does not contain any specific instructions for a particular patient. We disclaim all responsibility for the accuracy and reliability of this information. We`re not responsible for any damage.